Research suggests that drinking coffee — even in small amounts — may help reduce inflammation. Onderzoek heeft aangetoond dat 10 mg cafestol per dag gedurende 4 weken het totale cholesterolgehalte met 0,13 mmol/l verhoogt. Food Sci Biotechnol. HHS Is cafestol retained on the paper filter in the preparation of filter coffee? The R&G coffee had an average cafestol content of 603 mg/100 g R&G coffee with a slight reduction at higher roast intensities. Espresso contains more cafestol and kahweol than paper-filtered coffee, but because it is consumed in smaller amounts, it may not have much of an effect on people's LDL level. What About Metal Mesh Coffee Filters? Levels of cafestol, kahweol, and related diterpenoids in wild species of the coffee plant coffea B. de Roos, G. van der Weg, R. Urgert, P. van de Bovenkamp, A. Charrier, M.B. Physical characteristics of the paper filter and low cafestol content filter coffee brews Author: Rendón, Mery Yovana, dos Santos Scholz, Maria Brígida, Bragagnolo, Neura Source: Food research international 2018 v.108 pp. The Dark Side of Coffee. 1. To prepare your unfiltered cup of coffee, the attendant will boil your coffee instead of filtering it. The cholesterol-raising factor from coffee beans. New trends in coffee diterpenes research from technological to health aspects. There is a twist to this aspect of the coffee story, because cafestol and kahweol may also have some health benefits that are lost when they're filtered out. This explains why Scandinavian boiled coffee, Turkish coffee and French press (cafetière) coffee contain relatively high levels of cafestol and kahweol (6-12 mg/cup), while filtered coffee, percolated coffee and instant coffee contain low levels of cafestol and kahweol (0.2-0.6 mg/cup). Epub 2017 Aug 5. Copyright © 2018 Elsevier Ltd. All rights reserved. By continuing you agree to the use of cookies. 2020 Aug;134:109207. doi: 10.1016/j.foodres.2020.109207. Diterpenes are extracted by hot water but are retained by a paper filter. Some people think that removing caffeine from coffee might remove cafestol as well. The highest cafestol content was found in the lightly roasted coffee, and the coffee brew presented higher solids contents when the particle size of the coffee powder was below 500μm. Cafestol, a compound found in coffee, elevates cholesterol by hijacking a receptor in an intestinal pathway critical to its regulation, according to a recent article. Like many complex foods, not all of the compounds in coffee have been identified and fully studied, although researchers are working on it. This is the first study that reports the physical characteristics of paper filter and its importance to obtain filter coffee brew with low cafestol content. Previous studies involved filter coffee but the cellulose filter papers trap cafestol so levels are low containing only 0.1 mg. Diterpenes content was similar in espresso and paper-filtered brews. “There are certain types of coffee where the low-density lipoprotein (LDL) cholesterol levels may be a little higher,” he says, “like French press coffee, Turkish coffee and espresso.” How-ever, the anti-tumor mechanisms and molecular targets of cafestol and kahweol are poorly understood, especially in This site needs JavaScript to work properly. Abstract Some coffee brewing techniques raise the serum concentration of total and low-density-lipoprotein cholesterol in humans, whereas others do not. To build a better taco, you have to start with the foundation. Flour tortillas -- even the … A moka pot has two chambers. As Harvard’s Dr. van Dam explains, unfiltered coffee raises cholesterol: “Coffee contains a substance called cafestol that is a potent stimulator of LDL cholesterol levels. As they’ll be low on cafestol, there’s the minimum possibility of you having a high cholesterol level because of the same reason. Bij het filteren van koffie blijft cafestol achter in een papieren filter. ► Cafestol extraction yield is dependent on roast time and preparation method. Or any advice besides paper filters? Please enable it to take advantage of the complete set of features! Even so, additives to coffee, such as cream or sugar and other ingredients, can still increase the low-density … Low Dog tells me that the authors of the review wrote that patients with high cholesterol seem to be more sensitive to the cholesterol boosting properties of coffee. fee, while filtered coffee and instant coffee contain low levels of cafestol and kahweol [11,12]. Cafestol is de sterkste cholesterolverhogende stof die in ons dieet voorkomt. Believe it or not, how your coffee is brewed can make a huge difference to your heart health. All coffee brews presented low diterpene contents: 0.05 to 0.16 mg of kahweol and 0.11 to 0.14 mg of cafestol 50 mL-1. The diterpene retention capacities of the filters produced in the different countries were similar. Thanks Bottom line: LDL-P is the crucial data point. NIH In addition to cafestol, there are numerous other compounds in coffee which have an impact on its flavor, smell, and potential health risks. Ruiz del Castillo ML, Herraiz M, Blanch GP. J Agric Food Chem. Abstract We studied the effect of the coffee diterpene alcohols, cafestol and kahweol, on cholesterol metabolism in HepG2 cells.Uptake of 125 I-tyramine cellobiose–labeled LDL was decreased by 15% to 20% (P<.05) after 18 hours of preincubation with cafestol (20 μg/mL), whereas 25-hydroxycholesterol reduced uptake by 55% to 65% (P<.05). We use cookies to help provide and enhance our service and tailor content and ads. coffee brews contain 3–6 mg cafestol per cup, with variable but smaller amounts present in espresso cof-fee (3). #### Key messages . NLM eCollection 2019 Oct. Bułdak RJ, Hejmo T, Osowski M, Bułdak Ł, Kukla M, Polaniak R, Birkner E. Molecules. In an open randomized study, healthy male and female volunteers who drank coffee containing 148 mg cafestol and kahweol daily for 30 days exhibited a considerable rise in total cholesterol (average mean, 31.6%), low density lipoprotein (LDL) cholesterol (50.2%), and triglyceride concentrations (87%) versus the control group (Heckers et al., 1994). Back in December 2011 I wrote a post, ‘Cholesterol-y Coffee,’ about the sad, sad fact that drinking unfiltered coffee has been shown to raise cholesterol. Cafestol and kahweol are diter-penes that so far have been found only in coffee beans. Silva, Borges, Santos, and Alves (2012) also reported a chromatogram of a coffee brew with low intensity of ... (low-density lipoprotein) in such a way that can damage the heart. Food Chem Toxicol. USA.gov. Several types of coffee might have quite low amount of cafestol while some others might have higher amount of cafestol due to the certain processes that are given to the coffee bean. The cafestol and kahweol concentrations were low in the brews as can be seen from the low intensity of the peaks in the chromatogram in Fig. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. 1. In filtered coffee drinks such as drip brewed coffee, it is present in only negligible amounts, as the paper filter in drip filtered coffee retains the diterpenes. 2019 Aug 12;28(5):1287-1296. doi: 10.1007/s10068-019-00662-0. Rendón MY, Dos Santos Scholz MB, Bragagnolo N. Food Res Int. Daily coffee consumption is inversely associated with risk of type-2 diabetes (T2D). The low concentration of cafestol found in the Mocha preparation is presumed to be due to the fact that the coffee fines and coffee oil (containing the diterpenes) are not significantly transferred to the final brew and are retained in the water tank. ... Low density lipoprotein; Relatively high levels of cafestol and kahweol are present in unfiltered coffee drinks such as espresso, French press, boiled coffees or Turkish coffee/Greek coffee, while filtered coffee and instant coffee contain low levels of cafestol and kahweol [11, 12]. The diterpenes were extracted by direct saponification and quantified and identified by HPLC-DAD-MS/MS. This explains why Scandinavian boiled coffee, Turkish coffee and French press (cafetière) coffee contain relatively high levels of cafestol and kahweol (6-12 mg/cup), while filtered coffee, percolated coffee and instant coffee contain low levels of cafestol and kahweol (0.2-0.6 mg/cup). With more research, Professor Thelle and colleagues detected substances such as diterpenes kahweol and cafestol in coffee, that are responsible for the damage but can be removed by a filter. Relatively high levels of cafestol and kahweol are present in unfiltered coffee drinks such as espresso, French press, boiled coffees or Turkish coffee/Greek coffee, while filtered coffee and instant coffee contain low levels of cafestol and kahweol [11, 12]. The extraction yield of cafestol from roast and ground (R&G) coffee beans was evaluated using brews prepared by four brewing mechanisms (boiled, Turkish, French Press and Mocha Pot). ... Coffee contains cafestol, a compound that … Research into biological activity Caffeine was thought to be responsible, but studies have shown it has only a short-term effect on glucose and insulin, and decaffeinated coffee has the same effect as the regular version of the drink. Standardized to energy intake, these amounts are equal to 40, 8, or 0 cups of unfiltered coffee per 10 MJ per day in humans. Low pressure espresso. Katan Faculty of Science As there have been recent updates on this topic (see my The Cholesterol-Coffee Connection article on Answers.com) I thought it was a good time for a Going Lo-Co coffee-cholesterol update. Post SM(1), de Wit EC, Princen HM. Flour Tortillas. You see, the oils produced by coffee contain two decidedly unhealthy substances, cafestol and kahweol. Many wanted to know about instant coffee or coffee pods, addressed above. You could order an unfiltered cup of coffee, which includes espresso, Turkish coffees, and French press coffees. Cafestol, C 20 H 28 O 3, is a compound, specifically a diterpene alcohol, found in coffee beans.It is extracted during the coffee-brewing process and may be present in coffee beverages, depending on the preparation method. Copyright © 2020 Elsevier B.V. or its licensors or contributors. Italian espresso coffee contained 1.5 f 1.0 mg of cafestol per cup, five … Over a low heat, the pressure from the steam builds, forcing water up through the grounds into the top chamber to produce a concentrated “light” espresso. Dus koffie uit een filtermachine of koffiepad-apparaat bevat weinig cafestol. Analysis of the content of the diterpenes cafestol and kahweol in coffee brews. Scandinavian boiled coffee, Turkish coffee, and French press (cafetiere) coffee contain relatively high levels of cafestol and kahweol (6 to 12 mg/cup), while filtered coffee, percolated coffee, and instant coffee contain low levels of cafestol and kahweol (0.2 to 0.6 mg/cup) . Scientists in the Netherlands recently found that this type contains fatty chemicals known as cafestol and kahweol, which raise levels of dangerous fats in the blood. All coffee brews presented low diterpene contents: 0.05 to 0.16 mg of kahweol and 0.11 to 0.14 mg of cafestol 50 mL-1. Bij een gemiddeld cholesterolgehalte van 5,5 mmol/l betekent dat dus een verhoging met ongeveer 2%. In the brews, preparation method had an impact on cafestol concentration with French, Turkish and boiled preparation methods producing the highest cafestol concentrations. On the other hand, a low LDL-C and high LDL-P is bad news. Brewed up, low risk For the most part, you don’t have to worry about brewed coffee as it has no cholesterol in coffee beans, according to Dr. Bruemmer. The compounds in coffee associated with increased cholesterol levels are diterpines, specifically one called cafestol, which is present whether or not the coffee is decaffeinated. Even so, additives to coffee, such as cream or sugar and other ingredients, can still increase the low-density … Kahweol acetate and cafestol compounds shown to inhibit tumour growth in cells resistant to anti-cancer drugs Does anyone know of low-cafestol beans I can order for an espresso maker? Cafestol, a bioactive substance in coffee, increases glucose-stimulated insulin secretion in vitro and increases glucose uptake in human skeletal muscle cells. Cafestol may also act as an anticarcinogen, with some studies suggesting that there is an inverse association between coffee consumption and the de-velopment of colorectal cancer (9, 10). All coffee brews presented low diterpene contents: 0.05 to 0.16 mg of kahweol and 0.11 to 0.14 mg of cafestol 50 mL-1. Commercial low-fat and artificial creamers tend to be highly processed and may contain questionable ingredients. ► Cafestol concentration is reduced by extended roasting times. So, if you don’t want to leave drinking coffee, then you need to start having filtered coffees instead of the unfiltered one. Coffee made with filter paper has the least effect on cholesterol levels, as it removes most of the diterpenes. CONSUMPTION OF UNFILTERED coffee brews such as the Scandinavian-type boiled, cafetière (French-press), and Turkish coffee raises triacylglycerol and low-density lipoprotein (LDL)-cholesterol concentrations in humans (1– 3).A high intake of boiled coffee was associated with hypercholesterolemia and risk of coronary heart disease in Norway and Finland (1, 4, 5), and cafestol … … Some substances in coffee, oils called diterpenes (and one in particular, cafestol), have been associated with increased both total blood cholesterol and LDL (which stands for “low-density lipoprotein”) cholesterol, aka “bad” cholesterol, which may increase the risk of heart disease. Specifically LDL (bad) cholesterol. The attendant behind the counter will brew your coffee through a filter, which is typically made of paper. Cafestol, a diterpene present in unfiltered coffee brews such as Scandinavian boiled, Turkish, and cafetière coffee, is the most potent cholesterol-elevating compound known in the human diet. ApoE*3-Leiden, heterozygous low density lipoprotein-receptor (LDLR+/-) knockout, or wild-type (WT) C57BL/6 mice were fed a high- (0.05% wt/wt) or a low- (0.01% wt/wt) cafestol diet or a placebo diet for 8 weeks. After we posted this article, we got a number of queries from readers. 280-285 ISSN: 0963-9969 Subject: Several genes involved in cholesterol homeostasis have previously been shown to be targets of cafestol, including cholesterol 7-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid biosynthesis. High intakes of coffee brews rich in cafestol and kahweol may thus be responsible for unexplained increases in this enzyme activity in apparently healthy subjects. Research studies have uncovered important he… Clipboard, Search History, and several other advanced features are temporarily unavailable. In general, coffee brewed using a paper filter contains much less cafestol than unfiltered coffee. Coffee could slow or even stop prostate cancer growth, new study shows. Wie last heeft van een te hoog cholesterolgehalte kan hier beter niet te veel van binnen te krijgen. Both of these compounds tend to wreak havoc on your cholesterol and triglyceride levels. The cafestol and kahweol concentrations were low in the brews as can be seen from the low intensity of the peaks in the chromatogram in Fig. Author information: (1)Department of Endocrinology and Internal Medicine, Aarhus University Hospital , Tage-Hansens Gade 2, 8000 Aarhus C Denmark. This entry was posted in Heart Health and tagged best way to brew coffee, cafestol and coffee, coffee and heart health, does coffee cause heart disease, how to brew coffee, how to remove cafestol from my coffee, how to remove turpenes from coffee, is coffee good for my heart, is espresso bad for me, is French press coffee healthy, turpenes in coffee on September 21, 2018 by Taylor Donnini. The results showed that the porosity of the paper filter and the particle size of the ground roasted coffee were determinant factors in obtaining filter coffee brews with lower cafestol contents. Food Res Int. Moderate caffeine content. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. Cafestol extraction yield from different coffee brew mechanisms, https://doi.org/10.1016/j.foodres.2012.06.032. Instant coffee brew showed the lowest content of kahweol and absence of cafestol; this reduction was related to the production process of soluble coffee. Cafestol, the cholesterol-raising factor in boiled coffee, suppresses bile acid synthesis by downregulation of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase in rat hepatocytes. Silva, Borges, Santos, and Alves (2012) also reported a chromatogram of a coffee brew with low intensity of the peaks (cafestol and kahweol). Ive been advised to change my diet to reduce my LDL cholesterol level and some beans have lower cafestol which I understand can mitigate the risk. The cafestol content of the R&G coffee and the resulting brews was measured and extraction yield calculated. This indicates that of each 10 mg of cafestol in French‐press coffee consumed, 7 mg of cafestol is absorbed in the small intestines and available for raising serum cholesterol by about 0.13 mmol L … We hypothesized that cafestol can postpone development of T2D in KKAy mice. Instant coffee brew showed the lowest content of kahweol and absence of cafestol; this reduction was related to the production process of soluble coffee. Cholesterol; Diterpenes; Filter coffee; Kahweol; Paper filter; Porosity. The coffee diterpenes cafestol and kahweol raise serum cholesterol in humans. The cafestol amount that is found in coffee may vary depends on the type of coffee. The paper filters were physically characterized by measuring their grammage, and the fat permeation rate calculated in order to better understand the differences between the filters which allow one to obtain higher or lower diterpene contents. 2018 Dec 13;23(12):3309. doi: 10.3390/molecules23123309. Most studies have indicated that individuals consuming roughly 60 milligrams of cafestol (equivalent to 10 cups of unfiltered, French press coffee or 2 grams of coffee oil) may raise total cholesterol levels by an average of about 20%. Cafetiere coffee also raises low density lipoprotein cholesterol concentration and thus the risk of coronary heart disease. Thus, a sample of Catuai cultivar coffee with high cafestol content was roasted to a medium-light degree and used to prepare the brews in a 1:10 ratio (coffee powder to water). If researchers showed that cafestol and kahweol spiked LDL-P, I would consider switching back to filtered coffee. ► Cafestol brew concentration is dependent on roast time and preparation method. The extraction yield of cafestol was shown to be dependent on the brew mechanism and roasting time, with the lightest roast coffee prepared by French press or boiled preparations having the highest cafestol extraction yield (6.5% and 5.84%) and dark roast Mocha and Turkish preparations had the lowest extraction yields of 2.42% and 2.88% respectively. Biochemists analyzing coffee have found that instant coffee has low levels of cafestol and kahweol, similar to filtered coffee (Journal of Food Science and Technology, Nov. 2016). Research indicates that cafestol affects the body’s ability to metabolize and regulate cholesterol. Epub 2020 Apr 2. One way of brewing coffee increases the chance of heart attacks while another leads to longevity. COVID-19 is an emerging, rapidly evolving situation. The brewing temperature has little effect, so even cold-brewed coffee needs to be filtered or unfiltered depending on your cafestol preference. After we posted this article, we got a number of queries from readers.  |  1997 Jun;35(6):547-54. doi: 10.1016/s0278-6915(96)00123-8. The responsible factors are the diterpene lipids cafestol and kahweol, which make up about 1% (wt:wt) of coffee beans.  |  Cafestol may also act as an anticarcinogen, ... confined to the very low-density lipoprotein/low den-sity lipoprotein (VLDL/LDL) fraction, and they respond coffee brews contain 3–6 mg cafestol per cup, with variable but smaller amounts present in espresso cof-fee (3). Consumption of five cups per day of any of these coffee types could thus elevate serum cholesterol by 8-10 mgl dL. Coffee made with filter paper has the least effect on cholesterol levels, as it removes most of the diterpenes. Several types of coffee might have quite low amount of cafestol while some others might have higher amount of cafestol due to the certain processes that are given to the coffee bean. Some people think that removing caffeine from coffee might remove cafestol as well. The paper filters showed high fat permeability and grammages between 50.46 and 67.48 g/m2. Met name cafestol verhoogt het slechte (LDL) cholesterol in het bloed. Cafestol is present in highest quantity in unfiltered coffee drinks such as French press coffee or Turkish coffee/Greek coffee. This is the first study that reports the physical characteristics of paper filter and its importance to obtain filter coffee brew with low cafestol content. Rapid analysis of cholesterol-elevating compounds in coffee brews by off-line high-performance liquid chromatography/high-resolution gas chromatography. However, this is not true either. The cafestol amount that is found in coffee may vary depends on the type of coffee. So, make use of the filter paper. They are responsible for the raising of low density lipoproteins (LDL) and very low density lipoproteins (VLDL) brought about by drinking Scandinavian‐type boiled coffee [3,4], which contains 3–4 mg of … The results found in the literature concerning the effect of consuming filter coffee brews on increasing the blood cholesterol levels due to the presence of diterpenes, are divergent. Biochemists analyzing coffee have found that instant coffee has low levels of cafestol and kahweol, similar to filtered coffee (Journal of Food Science and Technology, Nov. 2016). Coffee’s cafestol has dual benefits Several genetic and life style risk factors have been linked to the development of type 2 diabetes, but drinking coffee has been shown to help prevent its onset. The mechanisms behind the cholesterol-raising ef-fect of cafestol, and possibly kahweol, are not known. In one study that measured the amount of cafestol in a cup of coffee brewed this way, investigators found that just 0.15% of the cafestol present in the unbrewed coffee grinds passed through to the brewed cup. The highest cafestol and kahweol concentrations were obtained using paper filters with micro perforations, considering similar sized paper filters. with filtered coffee my readings returned to “normal” Appendix 1. Mellbye FB(1), Jeppesen PB(1), Hermansen K(1), Gregersen S(1). Mechanisms of action of coffee bioactive components on lipid metabolism. Thus, a sample of Catuai cultivar coffee with high cafestol content was roasted to a medium-light degree and used to prepare the brews in a 1:10 ratio (coffee powder to water). Diterpenes content was similar in espresso and paper-filtered brews. The rest remained trapped in the spent coffee grinds (87.45%) and in the paper filter (12.41%). The Impact of Coffee and Its Selected Bioactive Compounds on the Development and Progression of Colorectal Cancer In Vivo and In Vitro. Pretty obvious really, as studies 10 have shown: the paper retains much of the grounds and hence the lipids; or, in the words of the researchers themselves: “…one can conclude that the greater part of the coffee cafestol is retained by the spent coffee, due to the low … One on the bottom for the water, one above it for the finished coffee. So, make use of the filter paper. Cafestol, a Bioactive Substance in Coffee, Stimulates Insulin Secretion and Increases Glucose Uptake in Muscle Cells: Studies in Vitro. If you order a typically cup of coffee you are likely ordering a filtered cup of coffee. Each 10 mg of cafestol consumed per day elevates cholesterol by 5 mg/dL (0.13 mmol/L). Author information: (1)Gaubius Laboratory, TNO-PG, Leiden, The Netherlands. The results showed that of the initial cafestol concentration present in the roasted coffee, the paper filter retained 12.41%, the spent coffee 87.45% and the brew 0.15%. In fact, having a high LDL-C (traditionally considered “dangerous”) and a low LDL-P puts you in a fairly low risk bracket. Two, drink coffee that is free of coffee oil. Coffee is extremely complex, chemically. Voor kinderen onder de 13 geldt het advies geen koffie te nemen en voor jongeren tussen de 13 en de 18 jaar maximaal 1 kopje, vanwege de cafeïne.  |  Coffee. But a paper filter traps most of the cafestol and kahweol, so coffee that's been filtered probably has little, if any, effect on cholesterol levels. Consumption of cafestol in coffee has been shown to produce both positive and negative health effects. Your morning cup of joe just might give your cholesterol level an unwanted jolt. American-style filtered coffee, in which hot water passes quickly through ground coffee in a paper filter, is the brewing method that gives you the least amount of cafestol, since most of this substance is left in the filter. 1999 Apr;47(4):1525-9. doi: 10.1021/jf980934v. Absorption of these coffee diterpenes expressed as a percentage of the amount consumed is about 70%. Coffee oils are naturally found in caffeinated and decaffeinated coffee. The cafestol and kahweol concentrations in the brews varied from 1.62 to 2.98 mg/L and from 0.73 to 1.96 mg/L, respectively. A potential site of action for cafestol may be the low … What About Metal Mesh Coffee Filters? Keywords: Cafestolis found in the oily fraction of coffee, and when you brew coffee with a paper filter, the cafestol gets left behind in the filter. press coffee 3.5 f 1.2 mg, and TurkisWGreek coffee 3.9 f 3.2 mg of cafestol per cup. trolled clinical trial (10). One, you can leave drinking the coffee. Thus, a sample of Catuai cultivar coffee with high cafestol content was roasted to a medium-light degree and used to prepare the brews in a 1:10 ratio (coffee powder to water). French press or Turkish coffee lets through cafestol, which raises levels of LDL, or “bad,” cholesterol. Vanwege de cafestol geldt het advies om per dag niet meer dan 2 tot 3 kopjes espresso of koffie van cups te drinken, niet meer dan 1 kopje gezet met een cafetière en geen kookkoffie. Thus the present research evaluated the diterpene (cafestol and kahweol) concentrations in filter coffee brews prepared with paper filters of different sizes, colors and origins (Brazil, Japan, The United States of America, Germany, France and the Netherlands), with and without micro perforations. The high diterpenes content, cafestol and kahweol, in coffee is inversely asso-ciated with reported risk of colorectal cancer [13]. Coffee is a popular beverage that’s rich in antioxidants and other beneficial compounds. The studies examined different types of unfiltered coffee, as well as coffee oil. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. 2017 Oct;100(Pt 1):798-803. doi: 10.1016/j.foodres.2017.08.013.

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